Lectins, Mitogenicity and Seed Germination: A Comparative Study with the Seeds of Telfairia occidentalis (Hook, F.) (Curcurbitaceae), Carica papaya (Linn) (Caricaceae) and Artocarpus communis (J.R. & G. Forst) (Moraceae)

The fate of lectins contained in the seeds of T. occidentalis, C. papaya and A. communis have been followed during the germinative process. Under the same culture conditions, the emergence of both the radicle and the plumule (the 3rd and 5th day; 18th and 20th and 12th and the 15th dayrespectively for T. occidentalis, C. papaya and A. communis) was preceded, 24 hours earlier, by the appearance of lectin in the developing tissues. The data suggest that the mitogenic lectins: Telfairia occidentalis Agglutinin (TOA) and Artocarpin accelerates the process of germinationrelative to that observed for seeds (C. papaya) containing the non-mitogenic lectins, Carici

Blockchain and SDN Architecture for Spectrum Management in Cellular Networks

Whereas 4G LTE networks have brought about an increase in data rates of mobile networks, they are unable to meet the capacity demands of future networks. Specifically, the centralized nature of the evolved packet core (EPC) makes the network non-scalable to match the exponential increase in number of wireless devices in addition to the complexities of diverse service requirements. The SDN concept has recently attracted a lot of research interest as a viable proposition for bringing about programmability and ease of network management while also offering flexibility for innovative network designs. However, current SDN implementations are not adapted to support business agreements that foster interoperability among mobile network operators (MNOs). This paper is an extended version of our earlier work and we intend to present a unified SDN and blockchain architecture with enhanced spectrum management features for enabling seamless user roaming capabilities between MNOs. Our simulation results show that users can experience no disruption in service with very minimal delay as they traverse between operators

Role of Lipids in Spheroidal High Density Lipoproteins

We study the structure and dynamics of spherical high density lipoprotein (HDL) particles through coarse-grained multi-microsecond molecular dynamics simulations. We simulate both a lipid droplet without the apolipoprotein A-I (apoA-I) and the full HDL particle including two apoA-I molecules surrounding the lipid compartment. The present models are the first ones among computational studies where the size and lipid composition of HDL are realistic, corresponding to human serum HDL. We focus on the role of lipids in HDL structure and dynamics. Particular attention is paid to the assembly of lipids and the influence of lipid-protein interactions on HDL properties. We find that the properties of lipids depend significantly on their location in the particle (core, intermediate region, surface). Unlike the hydrophobic core, the intermediate and surface regions are characterized by prominent conformational lipid order. Yet, not only the conformations but also the dynamics of lipids are found to be distinctly different in the different regions of HDL, highlighting the importance of dynamics in considering the functionalization of HDL. The structure of the lipid droplet close to the HDL-water interface is altered by the presence of apoA-Is, with most prominent changes being observed for cholesterol and polar lipids. For cholesterol, slow trafficking between the surface layer and the regimes underneath is observed. The lipid-protein interactions are strongest for cholesterol, in particular its interaction with hydrophobic residues of apoA-I. Our results reveal that not only hydrophobicity but also conformational entropy of the molecules are the driving forces in the formation of HDL structure. The results provide the first detailed structural model for HDL and its dynamics with and without apoA-I, and indicate how the interplay and competition between entropy and detailed interactions may be used in nanoparticle and drug design through self-assembly

Maternal and child health interventions in Nigeria: a systematic review of published studies from 1990 to 2014

BACKGROUND: Poor maternal and child health indicators have been reported in Nigeria since the 1990s. Many interventions have been instituted to reverse the trend and ensure that Nigeria is on track to achieve the Millennium Development Goals. This systematic review aims at describing and indirectly measuring the effect of the Maternal, Newborn, and Child Health (MNCH) interventions implemented in Nigeria from 1990 to 2014. METHODS: PubMed and ISI Web of Knowledge were searched from 1990 to April 2014 whereas POPLINE® was searched until 16 February 2015 to identify reports of interventions targeting Maternal, Newborn, and Child Health in Nigeria. Narrative and graphical synthesis was done by integrating the results of extracted studies with trends of maternal mortality ratio (MMR) and under five mortality (U5MR) derived from a joint point regression analysis using Nigeria Demographic and Health Survey data (1990-2013). This was supplemented by document analysis of policies, guidelines and strategies of the Federal Ministry of Health developed for Nigeria during the same period. RESULTS: We identified 66 eligible studies from 2,662 studies. Three interventions were deployed nationwide and the remainder at the regional level. Multiple study designs were employed in the enrolled studies: pre- and post-intervention or quasi-experimental (n = 40; 61%); clinical trials (n = 6;9%); cohort study or longitudinal evaluation (n = 3;5%); process/output/outcome evaluation (n = 17;26%). The national MMR shows a consistent reduction (Annual Percentage Change (APC) = -3.10%, 95% CI: -5.20 to -1.00 %) with marked decrease in the slope observed in the period with a cluster of published studies (2004-2014). Fifteen intervention studies specifically targeting under-five children were published during the 24 years of observation. A statistically insignificant downward trend in the U5MR was observed (APC = -1.25%, 95% CI: -4.70 to 2.40%) coinciding with publication of most of the studies and development of MNCH policies. CONCLUSIONS: The development of MNCH policies, implementation and publication of interventions corresponds with the downward trend of maternal and child mortality in Nigeria. This systematic review has also shown that more MNCH intervention research and publications of findings is required to generate local and relevant evidence

Comparative Study Of Electrical Conductivity And Salinity Of Soil Samples From Ibeno And Uyo Local Government Areas Of Akwa Ibom State, Nigeria

Soil samples were collected from Ibeno and Uyo Local Government Areas and were analyzed. The result reveals that soil samples from Ibeno have their salinities between the range 0.82

Spectroscopic analysis of ethanol produced by saccharomyces pastorianus in cassava starch hydrolyzate medium containing independent variable divalent cations saccharomyces pastorianus

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Behavioural and Anthropometric Risk Factors for Diabetes Mellitus among Newly Admitted Undergraduates in a Nigerian University

Background: Type 2 diabetes mellitus (DM) is fast becoming a global epidemic, and its revalence is increasing in children and young adults. The aim of the study was to identify young adults who had type 2 DM or impaired fasting glucose as well as those at risk of these conditions using anthropometric data and behavioral pattern. Methodology: Two hundred and twenty newly admitted undergraduates who were randomly selected during the registration process were involved in the study. Anthropometric parameters were measured while information on demographic details, medical history, and family history were obtained using a standard questionnaire. Fasting blood glucose was measured using the glucose oxidase method. Results: Two hundred and seven (94%) participants had serum glucose within reference range, 10 (4.6%) had impaired fasting glucose, and 3 (1.4%) had serum glucose >7.1 mmol/L, which is indicative of DM. A large number (91.4%) of individuals engaged in physical activity equivalent to a walk of at least 30 min/day. Most of them (93.2%) had body mass index <25.0 while 6.8% were overweight. One hundred and three participants (46.8%) indicated that they eat 3 or more servings of whole grain per day. Conclusion: Most of the participants are involved in healthy lifestyle. This has resulted in very low prevalence of impaired fasting glucose and type 2 DM among the group. It will be useful to follow up the group and note if they are able to maintain this trend since the risk of developing DM is known to increase with age.Keywords: Impaired fasting glucose, lifestyle, prevalence, type 2 diabetes mellitus, young adult